Best Cannabis Strains for Depression

Browse 47 cannabis strains commonly reported to help with depression. Compare THC/CBD levels, effects, terpene profiles, and growing information to find the right strain for your needs.

Medical Disclaimer: The information on this page is for educational purposes only and should not be considered medical advice. Cannabis is not FDA-approved for treating depression. Always consult a qualified healthcare professional before using cannabis for any medical condition. Individual results may vary significantly. Self-medicating without professional guidance can be harmful.

AK-47

Hybrid
THC 17–23%|CBD 0.1–0.3%|Easy
RelaxedHappyEuphoric

Amnesia Haze

Sativa
THC 20–25%|CBD 0.1–0.2%|Hard
EuphoricEnergeticCreative

Apple Fritter

Hybrid
THC 22–28%|CBD 0.1–0.2%|Moderate
EuphoricRelaxedHappy

Auto Amnesia Haze

Sativa
THC 16–21%|CBD 0.1–0.2%|Moderate
EuphoricCreativeEnergetic

Auto Girl Scout Cookies

Hybrid
THC 17–22%|CBD 0.1–0.2%|Easy
EuphoricHappyRelaxed

Auto Gorilla Glue

Hybrid
THC 18–24%|CBD 0.1–0.2%|Easy
RelaxedEuphoricHappy

Biscotti

Indica
THC 21–27%|CBD 0.1–0.2%|Moderate
RelaxedEuphoricHappy

Blue Dream

Hybrid
THC 17–24%|CBD 0.1–0.2%|Easy
HappyCreativeEuphoric

Bruce Banner #3

Hybrid
THC 24–30%|CBD 0.1–0.2%|Moderate
EuphoricCreativeEnergetic

Cereal Milk

Hybrid
THC 21–27%|CBD 0.1–0.2%|Moderate
HappyRelaxedEuphoric

Chemdawg

Hybrid
THC 20–26%|CBD 0.1–0.2%|Hard
EuphoricCreativeUplifted

Durban Poison

Sativa
THC 15–20%|CBD 0.1–0.2%|Easy
EnergeticUpliftedCreative

Gary Payton

Hybrid
THC 22–28%|CBD 0.1–0.2%|Hard
EuphoricRelaxedHappy

Gelato

Hybrid
THC 20–26%|CBD 0.1–0.2%|Moderate
RelaxedEuphoricHappy

Georgia Pie

Hybrid
THC 20–25%|CBD 0.1–0.2%|Moderate
HappyRelaxedEuphoric

Ghost Train Haze

Sativa
THC 25–32%|CBD 0.05–0.1%|Hard
EuphoricEnergeticCreative

Girl Scout Cookies

Hybrid
THC 22–28%|CBD 0.1–0.2%|Hard
EuphoricHappyRelaxed

Gorilla Cookies

Hybrid
THC 22–28%|CBD 0.1–0.2%|Moderate
EuphoricRelaxedHappy

Gorilla Glue #4

Hybrid
THC 25–32%|CBD 0.05–0.1%|Moderate
RelaxedEuphoricHappy

Green Crack

Sativa
THC 15–22%|CBD 0.1–0.2%|Easy
EnergeticFocusedHappy

Harlequin

Sativa
THC 4–10%|CBD 8–15%|Moderate
RelaxedClear-HeadedFocused

Hawaiian Haze

Sativa
THC 0.2–0.5%|CBD 14–18%|Easy
UpliftedHappyEnergetic

Headband

Hybrid
THC 20–27%|CBD 0.1–0.2%|Moderate
RelaxedEuphoricHappy

Jack Herer

Sativa
THC 18–24%|CBD 0.1–0.3%|Moderate
EnergeticCreativeFocused

Jealousy

Hybrid
THC 22–28%|CBD 0.1–0.2%|Moderate
RelaxedEuphoricHappy

Lemon Cherry Gelato

Hybrid
THC 22–28%|CBD 0.1–0.2%|Moderate
EuphoricRelaxedHappy

Lifter

Hybrid
THC 0.2–0.5%|CBD 14–20%|Easy
UpliftedFocusedCalm

MAC 1

Hybrid
THC 20–26%|CBD 0.1–0.2%|Hard
EuphoricCreativeRelaxed

Maui Wowie

Sativa
THC 14–20%|CBD 0.1–0.3%|Moderate
EnergeticHappyEuphoric

Mimosa

Hybrid
THC 19–27%|CBD 0.1–0.2%|Moderate
EnergeticHappyEuphoric

OG Kush

Hybrid
THC 20–26%|CBD 0.1–0.3%|Moderate
EuphoricRelaxedHappy

Permanent Marker

Hybrid
THC 21–28%|CBD 0.1–0.2%|Moderate
RelaxedEuphoricCreative

Pineapple Express

Hybrid
THC 17–24%|CBD 0.1–0.2%|Easy
HappyUpliftedEnergetic

Pink Runtz

Hybrid
THC 21–27%|CBD 0.1–0.2%|Hard
EuphoricHappyRelaxed

Purple Haze

Sativa
THC 17–22%|CBD 0.1–0.2%|Moderate
EuphoricCreativeEnergetic

Runtz

Hybrid
THC 19–29%|CBD 0.1–0.2%|Hard
EuphoricHappyRelaxed

Sour Diesel

Sativa
THC 19–25%|CBD 0.1–0.3%|Moderate
EnergeticEuphoricCreative

Strawberry Banana

Indica
THC 22–28%|CBD 0.1–0.2%|Moderate
HappyEuphoricRelaxed

Strawberry Cough

Sativa
THC 17–23%|CBD 0.1–0.2%|Moderate
HappyUpliftedEuphoric

Sunset Sherbet

Indica
THC 18–24%|CBD 0.1–0.2%|Moderate
RelaxedHappyEuphoric

Super Lemon Haze

Sativa
THC 18–25%|CBD 0.1–0.2%|Moderate
EnergeticHappyEuphoric

Tangie

Sativa
THC 19–22%|CBD 0.1–0.2%|Moderate
EuphoricCreativeUplifted

Thin Mint GSC

Hybrid
THC 21–28%|CBD 0.1–0.2%|Hard
EuphoricRelaxedHappy

Wedding Crasher

Hybrid
THC 20–25%|CBD 0.1–0.2%|Moderate
EuphoricRelaxedHappy

White Widow

Hybrid
THC 18–25%|CBD 0.1–0.2%|Easy
EuphoricCreativeEnergetic

Zkittlez

Indica
THC 18–24%|CBD 0.1–0.2%|Moderate
RelaxedHappyEuphoric

Zoap

Hybrid
THC 22–28%|CBD 0.1–0.2%|Hard
EuphoricRelaxedHappy

Disclaimer: Strain information is provided for educational purposes only. THC/CBD percentages are approximate ranges and vary by phenotype, growing conditions, and lab testing methodology. Cannabis is not a substitute for professional medical treatment. Always comply with your local laws regarding cannabis.